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Epigenetic Reprogramming via Synergistic Hypomethylation and Hypoxia Enhances the Therapeutic Efficacy of Mesenchymal Stem Cell Extracellular Vesicles for Bone Repair

Mesenchymal stem cells (MSCs) are a promising cell population for regenerative medicine applications, where paracrine signalling through the extracellular vesicles (EVs) regulates bone tissue homeostasis and development. MSCs are known to reside in low oxygen tension, which promotes osteogenic diffe...

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Detalles Bibliográficos
Autores principales:	Man, Kenny, Brunet, Mathieu Y., Lees, Rebecca, Peacock, Ben, Cox, Sophie C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142722/ https://www.ncbi.nlm.nih.gov/pubmed/37108726 http://dx.doi.org/10.3390/ijms24087564

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