Zinc(II)-Sterol Hydrazone Complex as a Potent Anti-Leishmania Agent: Synthesis, Characterization, and Insight into Its Mechanism of Antiparasitic Action

Searching for new alternatives for treating leishmaniasis, we present the synthesis, characterization, and biological evaluation against Leishmania amazonensis of the new ZnCl(2)(H3)(2) complex. H3 is 22-hydrazone-imidazoline-2-yl-chol-5-ene-3β-ol, a well-known bioactive molecule functioning as a st...

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Detalles Bibliográficos
Autores principales: Visbal, Gonzalo, Justo, Rodrigo M. S., dos Santos da Silva e Miranda, Gabrielle, Teixeira de Macedo Silva, Sara, de Souza, Wanderley, Rodrigues, Juliany Cola Fernandes, Navarro, Maribel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142724/
https://www.ncbi.nlm.nih.gov/pubmed/37111599
http://dx.doi.org/10.3390/pharmaceutics15041113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142724/
https://www.ncbi.nlm.nih.gov/pubmed/37111599
http://dx.doi.org/10.3390/pharmaceutics15041113

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