Versatile Solid Modifications of Multicomponent Pharmaceutical Salts: Novel Metformin–Rhein Salts Based on Advantage Complementary Strategy Design

This study aimed to develop an effective treatment for diabetes and diabetic complications, based on the advantage complementary strategy of drug–drug salt, by designing and synthesizing the multicomponent molecular salts containing metformin (MET) and rhein (RHE). Finally, the salts of MET–RHE (1:1...

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Detalles Bibliográficos
Autores principales: Yu, Mingchao, Liang, Meidai, An, Qi, Wang, Wenwen, Zhang, Baoxi, Yang, Shiying, Zhou, Jian, Yang, Xiuying, Yang, Dezhi, Zhang, Li, Du, Guanhua, Lu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142746/
https://www.ncbi.nlm.nih.gov/pubmed/37111681
http://dx.doi.org/10.3390/pharmaceutics15041196

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