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Film-Shaped Self-Powered Electro-Osmotic Micropump Array
This paper reports a new concept of a film-shaped micropump array for biomedical perfusion. The detailed concept, design, fabrication process, and performance evaluation using prototypes are described. In this micropump array, an open circuit potential (OCP) is generated by a planar biofuel cell (BF...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142748/ https://www.ncbi.nlm.nih.gov/pubmed/37421018 http://dx.doi.org/10.3390/mi14040785 |
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author | Yamanaka, Toshiro Arai, Fumihito |
author_facet | Yamanaka, Toshiro Arai, Fumihito |
author_sort | Yamanaka, Toshiro |
collection | PubMed |
description | This paper reports a new concept of a film-shaped micropump array for biomedical perfusion. The detailed concept, design, fabrication process, and performance evaluation using prototypes are described. In this micropump array, an open circuit potential (OCP) is generated by a planar biofuel cell (BFC), which in turn generates electro-osmotic flows (EOFs) in multiple through-holes arranged perpendicular to the micropump plane. The micropump array is thin and wireless, so it can be cut like postage stamps, easily installed in any small location, and can act as a planar micropump in solutions containing the biofuels glucose and oxygen. Perfusion at local sites are difficult with conventional techniques using multiple separate components such as micropumps and energy sources. This micropump array is expected to be applied to the perfusion of biological fluids in small locations near or inside cultured cells, cultured tissues, living organisms, and so on. |
format | Online Article Text |
id | pubmed-10142748 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101427482023-04-29 Film-Shaped Self-Powered Electro-Osmotic Micropump Array Yamanaka, Toshiro Arai, Fumihito Micromachines (Basel) Article This paper reports a new concept of a film-shaped micropump array for biomedical perfusion. The detailed concept, design, fabrication process, and performance evaluation using prototypes are described. In this micropump array, an open circuit potential (OCP) is generated by a planar biofuel cell (BFC), which in turn generates electro-osmotic flows (EOFs) in multiple through-holes arranged perpendicular to the micropump plane. The micropump array is thin and wireless, so it can be cut like postage stamps, easily installed in any small location, and can act as a planar micropump in solutions containing the biofuels glucose and oxygen. Perfusion at local sites are difficult with conventional techniques using multiple separate components such as micropumps and energy sources. This micropump array is expected to be applied to the perfusion of biological fluids in small locations near or inside cultured cells, cultured tissues, living organisms, and so on. MDPI 2023-03-31 /pmc/articles/PMC10142748/ /pubmed/37421018 http://dx.doi.org/10.3390/mi14040785 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Yamanaka, Toshiro Arai, Fumihito Film-Shaped Self-Powered Electro-Osmotic Micropump Array |
title | Film-Shaped Self-Powered Electro-Osmotic Micropump Array |
title_full | Film-Shaped Self-Powered Electro-Osmotic Micropump Array |
title_fullStr | Film-Shaped Self-Powered Electro-Osmotic Micropump Array |
title_full_unstemmed | Film-Shaped Self-Powered Electro-Osmotic Micropump Array |
title_short | Film-Shaped Self-Powered Electro-Osmotic Micropump Array |
title_sort | film-shaped self-powered electro-osmotic micropump array |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142748/ https://www.ncbi.nlm.nih.gov/pubmed/37421018 http://dx.doi.org/10.3390/mi14040785 |
work_keys_str_mv | AT yamanakatoshiro filmshapedselfpoweredelectroosmoticmicropumparray AT araifumihito filmshapedselfpoweredelectroosmoticmicropumparray |