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PreS1 Containing HBc VLPs for the Development of a Combined Therapeutic/Prophylactic Hepatitis B Vaccine
The available HBV vaccines based on the HBV surface protein are manufactured in yeasts and demonstrate excellent prophylactic but no therapeutic activity and are thus ineffective against chronic HBV infection. Five different HBV core proteins (HBc)—full length and C-terminally truncated—were used fo...
Autores principales: | Dishlers, Andris, Petrovskis, Ivars, Skrastina, Dace, Zarina, Ieva, Lieknina, Ilva, Jansons, Juris, Akopjana, Inara, Zakova, Jelena, Ose, Velta, Sominskaya, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142831/ https://www.ncbi.nlm.nih.gov/pubmed/37110395 http://dx.doi.org/10.3390/microorganisms11040972 |
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