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Echinochrome A Prevents Diabetic Nephropathy by Inhibiting the PKC-Iota Pathway and Enhancing Renal Mitochondrial Function in db/db Mice

Echinochrome A (EchA) is a natural bioproduct extracted from sea urchins, and is an active component of the clinical drug, Histochrome(®). EchA has antioxidant, anti-inflammatory, and antimicrobial effects. However, its effects on diabetic nephropathy (DN) remain poorly understood. In the present st...

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Detalles Bibliográficos
Autores principales: Pham, Trong Kha, Nguyen, To Hoai T., Yun, Hyeong Rok, Vasileva, Elena A., Mishchenko, Natalia P., Fedoreyev, Sergey A., Stonik, Valentin A., Vu, Thu Thi, Nguyen, Huy Quang, Cho, Sung Woo, Kim, Hyoung Kyu, Han, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142928/
https://www.ncbi.nlm.nih.gov/pubmed/37103361
http://dx.doi.org/10.3390/md21040222