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Tadalafil Rescues the p.M325T Mutant of Best1 Chloride Channel

Bestrophin 1 (Best1) is a chloride channel that localises to the plasma membrane of retinal pigment epithelium (RPE) cells. Mutations in the BEST1 gene are associated with a group of untreatable inherited retinal dystrophies (IRDs) called bestrophinopathies, caused by protein instability and loss-of...

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Detalles Bibliográficos
Autores principales:	Elverson, Kathleen, Warwicker, Jim, Freeman, Sally, Manson, Forbes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142963/ https://www.ncbi.nlm.nih.gov/pubmed/37110551 http://dx.doi.org/10.3390/molecules28083317

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