Injectable In-Situ Forming Depot Based on PLGA and PLGA-PEG-PLGA for Sustained-Release of Risperidone: In Vitro Evaluation and Pharmacokinetics in Rabbits

In the current research, novel drug delivery systems based on in situ forming gel (ISFG) (PLGA-PEG-PLGA) and in situ forming implant (ISFI) (PLGA) were developed for one-month risperidone delivery. In vitro release evaluation, pharmacokinetics, and histopathology studies of ISFI, ISFG, and Risperdal...

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Detalles Bibliográficos
Autores principales: Rezaeian Shiadeh, Seyedeh Nesa, Hadizadeh, Farzin, Khodaverdi, Elham, Gorji Valokola, Mahmoud, Rakhshani, Saleh, Kamali, Hossein, Nokhodchi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143068/
https://www.ncbi.nlm.nih.gov/pubmed/37111714
http://dx.doi.org/10.3390/pharmaceutics15041229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143068/
https://www.ncbi.nlm.nih.gov/pubmed/37111714
http://dx.doi.org/10.3390/pharmaceutics15041229

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