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The Acute and Chronic Effects of Resistance and Aerobic Exercise in Hemostatic Balance: A Brief Review

Hemostatic balance refers to the dynamic balance between blood clot formation (coagulation), blood clot dissolution (fibrinolysis), anticoagulation, and innate immunity. Although regular habitual exercise may lower the incidence of cardiovascular diseases (CVD) by improving an individual’s hemostati...

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Autores principales: Skouras, Apostolos Z., Antonakis-Karamintzas, Dimitrios, Tsantes, Andreas G., Triantafyllou, Athanasios, Papagiannis, Georgios, Tsolakis, Charilaos, Koulouvaris, Panagiotis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143125/
https://www.ncbi.nlm.nih.gov/pubmed/37104148
http://dx.doi.org/10.3390/sports11040074
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author Skouras, Apostolos Z.
Antonakis-Karamintzas, Dimitrios
Tsantes, Andreas G.
Triantafyllou, Athanasios
Papagiannis, Georgios
Tsolakis, Charilaos
Koulouvaris, Panagiotis
author_facet Skouras, Apostolos Z.
Antonakis-Karamintzas, Dimitrios
Tsantes, Andreas G.
Triantafyllou, Athanasios
Papagiannis, Georgios
Tsolakis, Charilaos
Koulouvaris, Panagiotis
author_sort Skouras, Apostolos Z.
collection PubMed
description Hemostatic balance refers to the dynamic balance between blood clot formation (coagulation), blood clot dissolution (fibrinolysis), anticoagulation, and innate immunity. Although regular habitual exercise may lower the incidence of cardiovascular diseases (CVD) by improving an individual’s hemostatic profile at rest and during exertion, vigorous exercise may increase the risk of sudden cardiac death and venous thromboembolism (VTE). This literature review aims to investigate the hemostatic system’s acute and chronic adaptive responses to different types of exercise in healthy and patient populations. Compared to athletes, sedentary healthy individuals demonstrate similar post-exercise responses in platelet function and coagulatory and fibrinolytic potential. However, hemostatic adaptations of patients with chronic diseases in regular training is a promising field. Despite the increased risk of thrombotic events during an acute bout of vigorous exercise, regular exposure to high-intensity exercise might desensitize exercise-induced platelet aggregation, moderate coagulatory parameters, and up-regulate fibrinolytic potential via increasing tissue plasminogen activator (tPA) and decreasing plasminogen activator inhibitor (PAI-1) response. Future research might focus on combining different types of exercise, manipulating each training characteristic (frequency, intensity, time, and volume), or investigating the minimal exercise dosage required to maintain hemostatic balance, especially in patients with various health conditions.
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spelling pubmed-101431252023-04-29 The Acute and Chronic Effects of Resistance and Aerobic Exercise in Hemostatic Balance: A Brief Review Skouras, Apostolos Z. Antonakis-Karamintzas, Dimitrios Tsantes, Andreas G. Triantafyllou, Athanasios Papagiannis, Georgios Tsolakis, Charilaos Koulouvaris, Panagiotis Sports (Basel) Review Hemostatic balance refers to the dynamic balance between blood clot formation (coagulation), blood clot dissolution (fibrinolysis), anticoagulation, and innate immunity. Although regular habitual exercise may lower the incidence of cardiovascular diseases (CVD) by improving an individual’s hemostatic profile at rest and during exertion, vigorous exercise may increase the risk of sudden cardiac death and venous thromboembolism (VTE). This literature review aims to investigate the hemostatic system’s acute and chronic adaptive responses to different types of exercise in healthy and patient populations. Compared to athletes, sedentary healthy individuals demonstrate similar post-exercise responses in platelet function and coagulatory and fibrinolytic potential. However, hemostatic adaptations of patients with chronic diseases in regular training is a promising field. Despite the increased risk of thrombotic events during an acute bout of vigorous exercise, regular exposure to high-intensity exercise might desensitize exercise-induced platelet aggregation, moderate coagulatory parameters, and up-regulate fibrinolytic potential via increasing tissue plasminogen activator (tPA) and decreasing plasminogen activator inhibitor (PAI-1) response. Future research might focus on combining different types of exercise, manipulating each training characteristic (frequency, intensity, time, and volume), or investigating the minimal exercise dosage required to maintain hemostatic balance, especially in patients with various health conditions. MDPI 2023-03-27 /pmc/articles/PMC10143125/ /pubmed/37104148 http://dx.doi.org/10.3390/sports11040074 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Skouras, Apostolos Z.
Antonakis-Karamintzas, Dimitrios
Tsantes, Andreas G.
Triantafyllou, Athanasios
Papagiannis, Georgios
Tsolakis, Charilaos
Koulouvaris, Panagiotis
The Acute and Chronic Effects of Resistance and Aerobic Exercise in Hemostatic Balance: A Brief Review
title The Acute and Chronic Effects of Resistance and Aerobic Exercise in Hemostatic Balance: A Brief Review
title_full The Acute and Chronic Effects of Resistance and Aerobic Exercise in Hemostatic Balance: A Brief Review
title_fullStr The Acute and Chronic Effects of Resistance and Aerobic Exercise in Hemostatic Balance: A Brief Review
title_full_unstemmed The Acute and Chronic Effects of Resistance and Aerobic Exercise in Hemostatic Balance: A Brief Review
title_short The Acute and Chronic Effects of Resistance and Aerobic Exercise in Hemostatic Balance: A Brief Review
title_sort acute and chronic effects of resistance and aerobic exercise in hemostatic balance: a brief review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143125/
https://www.ncbi.nlm.nih.gov/pubmed/37104148
http://dx.doi.org/10.3390/sports11040074
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