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Numerical Assessment of a Metal-Insulator-Metal Waveguide-Based Plasmonic Sensor System for the Recognition of Tuberculosis in Blood Plasma
In this paper, a numerical analysis of a plasmonic sensor based on a metal-insulator-metal (MIM) waveguide is conducted for the detection of tuberculosis (TB)-infected blood plasma. It is not straightforward to directly couple the light to the nanoscale MIM waveguide, because of which two Si(3)N(4)...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143205/ https://www.ncbi.nlm.nih.gov/pubmed/37420960 http://dx.doi.org/10.3390/mi14040729 |
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author | Butt, Muhammad A. |
author_facet | Butt, Muhammad A. |
author_sort | Butt, Muhammad A. |
collection | PubMed |
description | In this paper, a numerical analysis of a plasmonic sensor based on a metal-insulator-metal (MIM) waveguide is conducted for the detection of tuberculosis (TB)-infected blood plasma. It is not straightforward to directly couple the light to the nanoscale MIM waveguide, because of which two Si(3)N(4) mode converters are integrated with the plasmonic sensor. This allows the efficient conversion of the dielectric mode into a plasmonic mode, which propagates in the MIM waveguide via an input mode converter. At the output port, the plasmonic mode is converted back to the dielectric mode via the output mode converter. The proposed device is employed to detect TB-infected blood plasma. The refractive index of TB-infected blood plasma is slightly lower than that of normal blood plasma. Therefore, it is important to have a sensing device with high sensitivity. The sensitivity and figure of merit of the proposed device are ~900 nm/RIU and 11.84, respectively. |
format | Online Article Text |
id | pubmed-10143205 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101432052023-04-29 Numerical Assessment of a Metal-Insulator-Metal Waveguide-Based Plasmonic Sensor System for the Recognition of Tuberculosis in Blood Plasma Butt, Muhammad A. Micromachines (Basel) Article In this paper, a numerical analysis of a plasmonic sensor based on a metal-insulator-metal (MIM) waveguide is conducted for the detection of tuberculosis (TB)-infected blood plasma. It is not straightforward to directly couple the light to the nanoscale MIM waveguide, because of which two Si(3)N(4) mode converters are integrated with the plasmonic sensor. This allows the efficient conversion of the dielectric mode into a plasmonic mode, which propagates in the MIM waveguide via an input mode converter. At the output port, the plasmonic mode is converted back to the dielectric mode via the output mode converter. The proposed device is employed to detect TB-infected blood plasma. The refractive index of TB-infected blood plasma is slightly lower than that of normal blood plasma. Therefore, it is important to have a sensing device with high sensitivity. The sensitivity and figure of merit of the proposed device are ~900 nm/RIU and 11.84, respectively. MDPI 2023-03-25 /pmc/articles/PMC10143205/ /pubmed/37420960 http://dx.doi.org/10.3390/mi14040729 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Butt, Muhammad A. Numerical Assessment of a Metal-Insulator-Metal Waveguide-Based Plasmonic Sensor System for the Recognition of Tuberculosis in Blood Plasma |
title | Numerical Assessment of a Metal-Insulator-Metal Waveguide-Based Plasmonic Sensor System for the Recognition of Tuberculosis in Blood Plasma |
title_full | Numerical Assessment of a Metal-Insulator-Metal Waveguide-Based Plasmonic Sensor System for the Recognition of Tuberculosis in Blood Plasma |
title_fullStr | Numerical Assessment of a Metal-Insulator-Metal Waveguide-Based Plasmonic Sensor System for the Recognition of Tuberculosis in Blood Plasma |
title_full_unstemmed | Numerical Assessment of a Metal-Insulator-Metal Waveguide-Based Plasmonic Sensor System for the Recognition of Tuberculosis in Blood Plasma |
title_short | Numerical Assessment of a Metal-Insulator-Metal Waveguide-Based Plasmonic Sensor System for the Recognition of Tuberculosis in Blood Plasma |
title_sort | numerical assessment of a metal-insulator-metal waveguide-based plasmonic sensor system for the recognition of tuberculosis in blood plasma |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143205/ https://www.ncbi.nlm.nih.gov/pubmed/37420960 http://dx.doi.org/10.3390/mi14040729 |
work_keys_str_mv | AT buttmuhammada numericalassessmentofametalinsulatormetalwaveguidebasedplasmonicsensorsystemfortherecognitionoftuberculosisinbloodplasma |