Cargando…
Fungal β-Glucan-Based Nanotherapeutics: From Fabrication to Application
Fungal β-glucans are naturally occurring active macromolecules used in food and medicine due to their wide range of biological activities and positive health benefits. Significant research efforts have been devoted over the past decade to producing fungal β-glucan-based nanomaterials and promoting t...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143420/ https://www.ncbi.nlm.nih.gov/pubmed/37108930 http://dx.doi.org/10.3390/jof9040475 |
_version_ | 1785033847351541760 |
---|---|
author | Yang, Fan Cheung, Peter Chi Keung |
author_facet | Yang, Fan Cheung, Peter Chi Keung |
author_sort | Yang, Fan |
collection | PubMed |
description | Fungal β-glucans are naturally occurring active macromolecules used in food and medicine due to their wide range of biological activities and positive health benefits. Significant research efforts have been devoted over the past decade to producing fungal β-glucan-based nanomaterials and promoting their uses in numerous fields, including biomedicine. Herein, this review offers an up-to-date report on the synthetic strategies of common fungal β-glucan-based nanomaterials and preparation methods such as nanoprecipitation and emulsification. In addition, we highlight current examples of fungal β-glucan-based theranostic nanosystems and their prospective use for drug delivery and treatment in anti-cancer, vaccination, as well as anti-inflammatory treatments. It is anticipated that future advances in polysaccharide chemistry and nanotechnology will aid in the clinical translation of fungal β-glucan-based nanomaterials for the delivery of drugs and the treatment of illnesses. |
format | Online Article Text |
id | pubmed-10143420 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101434202023-04-29 Fungal β-Glucan-Based Nanotherapeutics: From Fabrication to Application Yang, Fan Cheung, Peter Chi Keung J Fungi (Basel) Review Fungal β-glucans are naturally occurring active macromolecules used in food and medicine due to their wide range of biological activities and positive health benefits. Significant research efforts have been devoted over the past decade to producing fungal β-glucan-based nanomaterials and promoting their uses in numerous fields, including biomedicine. Herein, this review offers an up-to-date report on the synthetic strategies of common fungal β-glucan-based nanomaterials and preparation methods such as nanoprecipitation and emulsification. In addition, we highlight current examples of fungal β-glucan-based theranostic nanosystems and their prospective use for drug delivery and treatment in anti-cancer, vaccination, as well as anti-inflammatory treatments. It is anticipated that future advances in polysaccharide chemistry and nanotechnology will aid in the clinical translation of fungal β-glucan-based nanomaterials for the delivery of drugs and the treatment of illnesses. MDPI 2023-04-15 /pmc/articles/PMC10143420/ /pubmed/37108930 http://dx.doi.org/10.3390/jof9040475 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Yang, Fan Cheung, Peter Chi Keung Fungal β-Glucan-Based Nanotherapeutics: From Fabrication to Application |
title | Fungal β-Glucan-Based Nanotherapeutics: From Fabrication to Application |
title_full | Fungal β-Glucan-Based Nanotherapeutics: From Fabrication to Application |
title_fullStr | Fungal β-Glucan-Based Nanotherapeutics: From Fabrication to Application |
title_full_unstemmed | Fungal β-Glucan-Based Nanotherapeutics: From Fabrication to Application |
title_short | Fungal β-Glucan-Based Nanotherapeutics: From Fabrication to Application |
title_sort | fungal β-glucan-based nanotherapeutics: from fabrication to application |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143420/ https://www.ncbi.nlm.nih.gov/pubmed/37108930 http://dx.doi.org/10.3390/jof9040475 |
work_keys_str_mv | AT yangfan fungalbglucanbasednanotherapeuticsfromfabricationtoapplication AT cheungpeterchikeung fungalbglucanbasednanotherapeuticsfromfabricationtoapplication |