Transthyretin Stabilizers and Seeding Inhibitors as Therapies for Amyloid Transthyretin Cardiomyopathy

Transthyretin (TTR) amyloid cardiomyopathy (ATTR-CM) is a progressive and increasingly recognized cause of heart failure which is associated with high mortality and morbidity. ATTR-CM is characterized by the misfolding of TTR monomers and their deposition within the myocardium as amyloid fibrils. Th...

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Detalles Bibliográficos
Autores principales: Morfino, Paolo, Aimo, Alberto, Vergaro, Giuseppe, Sanguinetti, Chiara, Castiglione, Vincenzo, Franzini, Maria, Perrone, Marco Alfonso, Emdin, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143494/
https://www.ncbi.nlm.nih.gov/pubmed/37111614
http://dx.doi.org/10.3390/pharmaceutics15041129

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