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Alginate-Based Materials Loaded with Nanoparticles in Wound Healing
Alginate is a naturally derived polysaccharide widely applied in drug delivery, as well as regenerative medicine, tissue engineering and wound care. Due to its excellent biocompatibility, low toxicity, and the ability to absorb a high amount of exudate, it is widely used in modern wound dressings. N...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143535/ https://www.ncbi.nlm.nih.gov/pubmed/37111628 http://dx.doi.org/10.3390/pharmaceutics15041142 |
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author | Froelich, Anna Jakubowska, Emilia Wojtyłko, Monika Jadach, Barbara Gackowski, Michał Gadziński, Piotr Napierała, Olga Ravliv, Yulia Osmałek, Tomasz |
author_facet | Froelich, Anna Jakubowska, Emilia Wojtyłko, Monika Jadach, Barbara Gackowski, Michał Gadziński, Piotr Napierała, Olga Ravliv, Yulia Osmałek, Tomasz |
author_sort | Froelich, Anna |
collection | PubMed |
description | Alginate is a naturally derived polysaccharide widely applied in drug delivery, as well as regenerative medicine, tissue engineering and wound care. Due to its excellent biocompatibility, low toxicity, and the ability to absorb a high amount of exudate, it is widely used in modern wound dressings. Numerous studies indicate that alginate applied in wound care can be enhanced with the incorporation of nanoparticles, revealing additional properties beneficial in the healing process. Among the most extensively explored materials, composite dressings with alginate loaded with antimicrobial inorganic nanoparticles can be mentioned. However, other types of nanoparticles with antibiotics, growth factors, and other active ingredients are also investigated. This review article focuses on the most recent findings regarding novel alginate-based materials loaded with nanoparticles and their applicability as wound dressings, with special attention paid to the materials of potential use in the treatment of chronic wounds. |
format | Online Article Text |
id | pubmed-10143535 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101435352023-04-29 Alginate-Based Materials Loaded with Nanoparticles in Wound Healing Froelich, Anna Jakubowska, Emilia Wojtyłko, Monika Jadach, Barbara Gackowski, Michał Gadziński, Piotr Napierała, Olga Ravliv, Yulia Osmałek, Tomasz Pharmaceutics Review Alginate is a naturally derived polysaccharide widely applied in drug delivery, as well as regenerative medicine, tissue engineering and wound care. Due to its excellent biocompatibility, low toxicity, and the ability to absorb a high amount of exudate, it is widely used in modern wound dressings. Numerous studies indicate that alginate applied in wound care can be enhanced with the incorporation of nanoparticles, revealing additional properties beneficial in the healing process. Among the most extensively explored materials, composite dressings with alginate loaded with antimicrobial inorganic nanoparticles can be mentioned. However, other types of nanoparticles with antibiotics, growth factors, and other active ingredients are also investigated. This review article focuses on the most recent findings regarding novel alginate-based materials loaded with nanoparticles and their applicability as wound dressings, with special attention paid to the materials of potential use in the treatment of chronic wounds. MDPI 2023-04-04 /pmc/articles/PMC10143535/ /pubmed/37111628 http://dx.doi.org/10.3390/pharmaceutics15041142 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Froelich, Anna Jakubowska, Emilia Wojtyłko, Monika Jadach, Barbara Gackowski, Michał Gadziński, Piotr Napierała, Olga Ravliv, Yulia Osmałek, Tomasz Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
title | Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
title_full | Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
title_fullStr | Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
title_full_unstemmed | Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
title_short | Alginate-Based Materials Loaded with Nanoparticles in Wound Healing |
title_sort | alginate-based materials loaded with nanoparticles in wound healing |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143535/ https://www.ncbi.nlm.nih.gov/pubmed/37111628 http://dx.doi.org/10.3390/pharmaceutics15041142 |
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