Cargando…
Effects of a Losartan-Antioxidant Hybrid (GGN1231) on Vascular and Cardiac Health in an Experimental Model of Chronic Renal Failure
Drugs providing antihypertensive and protective cardiovascular actions are of clinical interest in controlling cardiovascular events and slowing the progression of kidney disease. We studied the effect of a hybrid compound, GGN1231 (derived from losartan in which a powerful antioxidant was attached)...
Autores principales: | Martínez-Arias, Laura, Fernández-Villabrille, Sara, Alonso-Montes, Cristina, García-Navazo, Gonzalo, Ruíz-Torres, María P., Alajarín, Ramón, Alvarez-Builla, Julio, Gutiérrez-Calabres, Elena, Vaquero-López, Juan José, Carrillo-López, Natalia, Rodríguez-Puyol, Diego, Cannata-Andía, Jorge B., Panizo, Sara, Naves-Díaz, Manuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143556/ https://www.ncbi.nlm.nih.gov/pubmed/37111038 http://dx.doi.org/10.3390/nu15081820 |
Ejemplares similares
-
Phosphorus May Induce Phenotypic Transdifferentiation of Vascular Smooth Muscle Cells through the Reduction of microRNA-145
por: Fernández-Villabrille, Sara, et al.
Publicado: (2023) -
Fibrosis in Chronic Kidney Disease: Pathogenesis and Consequences
por: Panizo, Sara, et al.
Publicado: (2021) -
Experimental Models to Study Diabetes Mellitus and Its Complications: Limitations and New Opportunities
por: Martín-Carro, Beatriz, et al.
Publicado: (2023) -
MicroRNA-145 and microRNA-486 are potential serum biomarkers for vascular calcification
por: Fernández-Villabrille, Sara, et al.
Publicado: (2023) -
Role of Klotho and AGE/RAGE-Wnt/β-Catenin Signalling Pathway on the Development of Cardiac and Renal Fibrosis in Diabetes
por: Martín-Carro, Beatriz, et al.
Publicado: (2023)