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A Dual Therapy of Nanostructured Lipid Carrier Loaded with Teriflunomide—A Dihydro-Orotate Dehydrogenase Inhibitor and an miR-155-Antagomir in Cuprizone-Induced C57BL/6J Mouse

The effective treatment of central nervous system (CNS) disorders such as multiple sclerosis (MS) has been challenging due to the limited ability of therapeutic agents to cross the blood–brain barrier (BBB). In this study, we investigated the potential of nanocarrier systems to deliver miR-155-antag...

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Detalles Bibliográficos
Autores principales: Koduru, Trideva Sastri, Gupta, Vishal N., Veeranna, Balamuralidhara, Seetharaman, Shanmuganathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143733/
https://www.ncbi.nlm.nih.gov/pubmed/37111739
http://dx.doi.org/10.3390/pharmaceutics15041254