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Glaucoma and Systemic Disease

Glaucoma is the leading cause of irreversible blindness in the world. Due to its potential to cause permanent vision loss, it is important to understand how systemic conditions and their respective treatments can be associated with or increase the risk for developing glaucoma. In this review, we exa...

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Detalles Bibliográficos
Autores principales: Hsu, Eugene, Desai, Manishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143901/
https://www.ncbi.nlm.nih.gov/pubmed/37109547
http://dx.doi.org/10.3390/life13041018
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author Hsu, Eugene
Desai, Manishi
author_facet Hsu, Eugene
Desai, Manishi
author_sort Hsu, Eugene
collection PubMed
description Glaucoma is the leading cause of irreversible blindness in the world. Due to its potential to cause permanent vision loss, it is important to understand how systemic conditions and their respective treatments can be associated with or increase the risk for developing glaucoma. In this review, we examined the literature for up-to-date discussions and provided commentary on glaucoma, its pathophysiology, and associated risk factors. We discuss systemic diseases and the impact, risk, and mechanism for developing glaucoma, including pharmacologically induced glaucoma; inflammatory and auto-immune conditions; infectious, dermatologic, cardiovascular, pulmonary, renal, urologic, neurologic, psychiatric and systemic malignancies: intraocular tumors; as well as pediatric, and genetic conditions. The goal of our discussion of systemic conditions including their commonality, mechanisms, treatments, and associations with developing glaucoma is to emphasize the importance of ocular examinations and follow-up with the multidisciplinary teams involved in the care of each patient to prevent unnecessary vision-loss.
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spelling pubmed-101439012023-04-29 Glaucoma and Systemic Disease Hsu, Eugene Desai, Manishi Life (Basel) Review Glaucoma is the leading cause of irreversible blindness in the world. Due to its potential to cause permanent vision loss, it is important to understand how systemic conditions and their respective treatments can be associated with or increase the risk for developing glaucoma. In this review, we examined the literature for up-to-date discussions and provided commentary on glaucoma, its pathophysiology, and associated risk factors. We discuss systemic diseases and the impact, risk, and mechanism for developing glaucoma, including pharmacologically induced glaucoma; inflammatory and auto-immune conditions; infectious, dermatologic, cardiovascular, pulmonary, renal, urologic, neurologic, psychiatric and systemic malignancies: intraocular tumors; as well as pediatric, and genetic conditions. The goal of our discussion of systemic conditions including their commonality, mechanisms, treatments, and associations with developing glaucoma is to emphasize the importance of ocular examinations and follow-up with the multidisciplinary teams involved in the care of each patient to prevent unnecessary vision-loss. MDPI 2023-04-15 /pmc/articles/PMC10143901/ /pubmed/37109547 http://dx.doi.org/10.3390/life13041018 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hsu, Eugene
Desai, Manishi
Glaucoma and Systemic Disease
title Glaucoma and Systemic Disease
title_full Glaucoma and Systemic Disease
title_fullStr Glaucoma and Systemic Disease
title_full_unstemmed Glaucoma and Systemic Disease
title_short Glaucoma and Systemic Disease
title_sort glaucoma and systemic disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143901/
https://www.ncbi.nlm.nih.gov/pubmed/37109547
http://dx.doi.org/10.3390/life13041018
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