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Tropoelastin-Pretreated Exosomes from Adipose-Derived Stem Cells Improve the Synthesis of Cartilage Matrix and Alleviate Osteoarthritis

Mesenchymal stem cells (MSCs) have recently been widely used to treat osteoarthritis (OA). Our prior research shows that tropoelastin (TE) increases MSC activity and protects knee cartilage from OA-related degradation. The underlying mechanism might be that TE regulates the paracrine of MSCs. Exosom...

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Detalles Bibliográficos
Autores principales: Meng, Shuo, Tang, Cong, Deng, Muhai, Yuan, Jie, Fan, Yanli, Gao, Shasha, Feng, Yong, Yang, Junjun, Chen, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143921/
https://www.ncbi.nlm.nih.gov/pubmed/37103293
http://dx.doi.org/10.3390/jfb14040203