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Reduced Graphene Oxide as a Platform for the Immobilization of Amino-Cyclodextrins
In the present work, we reported on a method to combine amino β-cyclodextrins (CD1) with reduced graphene oxide (obtained by the electrochemical reduction of graphene oxide, erGO) to produce a glassy carbon electrode (GCE) modified with both CD1 and erGO (CD1-erGO/GCE). This procedure avoids the use...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143922/ https://www.ncbi.nlm.nih.gov/pubmed/37420979 http://dx.doi.org/10.3390/mi14040746 |
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author | Villalobos, Elias Marco, José F. Yáñez, Claudia |
author_facet | Villalobos, Elias Marco, José F. Yáñez, Claudia |
author_sort | Villalobos, Elias |
collection | PubMed |
description | In the present work, we reported on a method to combine amino β-cyclodextrins (CD1) with reduced graphene oxide (obtained by the electrochemical reduction of graphene oxide, erGO) to produce a glassy carbon electrode (GCE) modified with both CD1 and erGO (CD1-erGO/GCE). This procedure avoids the use of organic solvents such as hydrazine or long reaction times and high temperatures. The material combining both CD1 and erGO (CD1-erGO/GCE) was characterized by SEM, ATR-FTIR, Raman, XPS, and electrochemical techniques. As proof-of-concept, the determination of the pesticide carbendazim was carried out. The spectroscopic measurements, especially XPS, proved that CD1 was covalently attached to the surface of the erGO/GCE electrode. The attachment of cyclodextrin at the reduced graphene oxide produced an increase in the electrochemical behavior of the electrode. The cyclodextrin-functionalized reduced graphene oxide, CD1-erGO/GCE, showed a larger sensitivity (1.01 μA/μM) and a lower limit of detection for carbendazim (LOD = 0.50 μM) compared with the non-functionalized material, erGO/GCE, (sensitivity = 0.63 μA/μM and LOD = 4.32 μM, respectively). Overall, the results of the present work show that this simple method is suitable to attach cyclodextrins to graphene oxide, maintaining their inclusion abilities. |
format | Online Article Text |
id | pubmed-10143922 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101439222023-04-29 Reduced Graphene Oxide as a Platform for the Immobilization of Amino-Cyclodextrins Villalobos, Elias Marco, José F. Yáñez, Claudia Micromachines (Basel) Article In the present work, we reported on a method to combine amino β-cyclodextrins (CD1) with reduced graphene oxide (obtained by the electrochemical reduction of graphene oxide, erGO) to produce a glassy carbon electrode (GCE) modified with both CD1 and erGO (CD1-erGO/GCE). This procedure avoids the use of organic solvents such as hydrazine or long reaction times and high temperatures. The material combining both CD1 and erGO (CD1-erGO/GCE) was characterized by SEM, ATR-FTIR, Raman, XPS, and electrochemical techniques. As proof-of-concept, the determination of the pesticide carbendazim was carried out. The spectroscopic measurements, especially XPS, proved that CD1 was covalently attached to the surface of the erGO/GCE electrode. The attachment of cyclodextrin at the reduced graphene oxide produced an increase in the electrochemical behavior of the electrode. The cyclodextrin-functionalized reduced graphene oxide, CD1-erGO/GCE, showed a larger sensitivity (1.01 μA/μM) and a lower limit of detection for carbendazim (LOD = 0.50 μM) compared with the non-functionalized material, erGO/GCE, (sensitivity = 0.63 μA/μM and LOD = 4.32 μM, respectively). Overall, the results of the present work show that this simple method is suitable to attach cyclodextrins to graphene oxide, maintaining their inclusion abilities. MDPI 2023-03-28 /pmc/articles/PMC10143922/ /pubmed/37420979 http://dx.doi.org/10.3390/mi14040746 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Villalobos, Elias Marco, José F. Yáñez, Claudia Reduced Graphene Oxide as a Platform for the Immobilization of Amino-Cyclodextrins |
title | Reduced Graphene Oxide as a Platform for the Immobilization of Amino-Cyclodextrins |
title_full | Reduced Graphene Oxide as a Platform for the Immobilization of Amino-Cyclodextrins |
title_fullStr | Reduced Graphene Oxide as a Platform for the Immobilization of Amino-Cyclodextrins |
title_full_unstemmed | Reduced Graphene Oxide as a Platform for the Immobilization of Amino-Cyclodextrins |
title_short | Reduced Graphene Oxide as a Platform for the Immobilization of Amino-Cyclodextrins |
title_sort | reduced graphene oxide as a platform for the immobilization of amino-cyclodextrins |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143922/ https://www.ncbi.nlm.nih.gov/pubmed/37420979 http://dx.doi.org/10.3390/mi14040746 |
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