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Molecular Interactions between APIs and Enteric Polymeric Excipients in Solid Dispersion: Insights from Molecular Simulations and Experiments
Solid dispersion of poorly soluble APIs is known to be a promising strategy to improve dissolution and oral bioavailability. To facilitate the development and commercialization of a successful solid dispersion formulation, understanding of intermolecular interactions between APIs and polymeric carri...
Autores principales: | Gupta, Krishna M., Chin, Xavier, Kanaujia, Parijat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10143979/ https://www.ncbi.nlm.nih.gov/pubmed/37111649 http://dx.doi.org/10.3390/pharmaceutics15041164 |
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