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Optimal Serum 25(OH)D Levels and Vitamin D Intake in Korean Postmenopausal Women
Vitamin D plays a crucial role in regulating the growth and maintenance of the musculoskeletal system. Postmenopausal women are vulnerable to bone fractures because of the decrease in bone mineral density (BMD). Therefore, this study aimed to identify the determinants that influence BMD and the 25(O...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144100/ https://www.ncbi.nlm.nih.gov/pubmed/37111073 http://dx.doi.org/10.3390/nu15081856 |
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author | Shin, Hye Ran Lee, Ye Jin Ly, Sun Yung |
author_facet | Shin, Hye Ran Lee, Ye Jin Ly, Sun Yung |
author_sort | Shin, Hye Ran |
collection | PubMed |
description | Vitamin D plays a crucial role in regulating the growth and maintenance of the musculoskeletal system. Postmenopausal women are vulnerable to bone fractures because of the decrease in bone mineral density (BMD). Therefore, this study aimed to identify the determinants that influence BMD and the 25(OH)D levels in Korean postmenopausal women. This study collected general and dietary intake information, measured biochemical indices, and conducted BMD tests in 96 postmenopausal women residing in a metropolitan area in Korea. This study analyzed factors that influenced serum 25-hydroxyvitamin D (25(OH)D) and BMD, as well as the correlation between the intact parathyroid hormone (iPTH) and serum 25(OH)D levels. The serum 25(OH)D levels increased by 0.226 ng/mL in the summertime, 0.314 ng/mL in the wintertime, and 0.370 ng/mL on annual average when vitamin D intake rose by 1 µg/1000 kcal. When the serum 25(OH)D levels were ≥18.9 ng/mL, the iPTH levels did not rapidly increase. To maintain the serum 25(OH)D levels at ≥18.9 ng/mL, a daily vitamin D intake of ≥13.21 µg was required. Consequently, consuming vitamin D-fortified foods or vitamin D supplements is necessary to improve both bone health and vitamin D nutritional status. |
format | Online Article Text |
id | pubmed-10144100 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101441002023-04-29 Optimal Serum 25(OH)D Levels and Vitamin D Intake in Korean Postmenopausal Women Shin, Hye Ran Lee, Ye Jin Ly, Sun Yung Nutrients Article Vitamin D plays a crucial role in regulating the growth and maintenance of the musculoskeletal system. Postmenopausal women are vulnerable to bone fractures because of the decrease in bone mineral density (BMD). Therefore, this study aimed to identify the determinants that influence BMD and the 25(OH)D levels in Korean postmenopausal women. This study collected general and dietary intake information, measured biochemical indices, and conducted BMD tests in 96 postmenopausal women residing in a metropolitan area in Korea. This study analyzed factors that influenced serum 25-hydroxyvitamin D (25(OH)D) and BMD, as well as the correlation between the intact parathyroid hormone (iPTH) and serum 25(OH)D levels. The serum 25(OH)D levels increased by 0.226 ng/mL in the summertime, 0.314 ng/mL in the wintertime, and 0.370 ng/mL on annual average when vitamin D intake rose by 1 µg/1000 kcal. When the serum 25(OH)D levels were ≥18.9 ng/mL, the iPTH levels did not rapidly increase. To maintain the serum 25(OH)D levels at ≥18.9 ng/mL, a daily vitamin D intake of ≥13.21 µg was required. Consequently, consuming vitamin D-fortified foods or vitamin D supplements is necessary to improve both bone health and vitamin D nutritional status. MDPI 2023-04-12 /pmc/articles/PMC10144100/ /pubmed/37111073 http://dx.doi.org/10.3390/nu15081856 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Shin, Hye Ran Lee, Ye Jin Ly, Sun Yung Optimal Serum 25(OH)D Levels and Vitamin D Intake in Korean Postmenopausal Women |
title | Optimal Serum 25(OH)D Levels and Vitamin D Intake in Korean Postmenopausal Women |
title_full | Optimal Serum 25(OH)D Levels and Vitamin D Intake in Korean Postmenopausal Women |
title_fullStr | Optimal Serum 25(OH)D Levels and Vitamin D Intake in Korean Postmenopausal Women |
title_full_unstemmed | Optimal Serum 25(OH)D Levels and Vitamin D Intake in Korean Postmenopausal Women |
title_short | Optimal Serum 25(OH)D Levels and Vitamin D Intake in Korean Postmenopausal Women |
title_sort | optimal serum 25(oh)d levels and vitamin d intake in korean postmenopausal women |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144100/ https://www.ncbi.nlm.nih.gov/pubmed/37111073 http://dx.doi.org/10.3390/nu15081856 |
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