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Nutritional Status Differs by Prescription Opioid Use among Women of Reproductive Age: NHANES 1999–2018

Prescription opioid use among pregnant women has increased in recent years. Prenatal exposure to opioids and poor nutrition can both negatively impact maternal–fetal outcomes. The objective of this study was to characterize the nutrition and health status of reproductive-age women taking prescriptio...

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Autores principales: Hohman, Emily E., Corr, Tammy E., Kawasaki, Sarah, Savage, Jennifer S., Symons Downs, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144164/
https://www.ncbi.nlm.nih.gov/pubmed/37111110
http://dx.doi.org/10.3390/nu15081891
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author Hohman, Emily E.
Corr, Tammy E.
Kawasaki, Sarah
Savage, Jennifer S.
Symons Downs, Danielle
author_facet Hohman, Emily E.
Corr, Tammy E.
Kawasaki, Sarah
Savage, Jennifer S.
Symons Downs, Danielle
author_sort Hohman, Emily E.
collection PubMed
description Prescription opioid use among pregnant women has increased in recent years. Prenatal exposure to opioids and poor nutrition can both negatively impact maternal–fetal outcomes. The objective of this study was to characterize the nutrition and health status of reproductive-age women taking prescription opioids, compared to women not taking opioids. Using NHANES 1999–2018 data, non-pregnant women aged 20–44 years were classified as taking a prescription opioid in the last 30 days (n = 404) or unexposed controls (n = 7234). Differences in anthropometric, cardiovascular, hematologic, and micronutrient status indicators between opioid-exposed and unexposed women were examined. Opioid-exposed women were older, had lower income and education, and were more likely to be non-Hispanic White, to smoke, and to have chronic health conditions compared to unexposed women. In unadjusted analyses, several nutrition and health markers were significantly different between opioid exposure groups. After controlling for covariates, women taking opioids had higher odds of Class II (OR = 1.6, 95% CI = 1.1–2.3) or III obesity (OR = 1.6, 95% CI = 1.1–2.5), and lower levels of serum folate, iron, and transferrin saturation. Reproductive-age women taking prescription opioids may be at risk for poorer nutritional and cardiometabolic health. Future research is needed to explore whether nutritional status impacts maternal–fetal outcomes for women exposed to opioids during pregnancy.
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spelling pubmed-101441642023-04-29 Nutritional Status Differs by Prescription Opioid Use among Women of Reproductive Age: NHANES 1999–2018 Hohman, Emily E. Corr, Tammy E. Kawasaki, Sarah Savage, Jennifer S. Symons Downs, Danielle Nutrients Article Prescription opioid use among pregnant women has increased in recent years. Prenatal exposure to opioids and poor nutrition can both negatively impact maternal–fetal outcomes. The objective of this study was to characterize the nutrition and health status of reproductive-age women taking prescription opioids, compared to women not taking opioids. Using NHANES 1999–2018 data, non-pregnant women aged 20–44 years were classified as taking a prescription opioid in the last 30 days (n = 404) or unexposed controls (n = 7234). Differences in anthropometric, cardiovascular, hematologic, and micronutrient status indicators between opioid-exposed and unexposed women were examined. Opioid-exposed women were older, had lower income and education, and were more likely to be non-Hispanic White, to smoke, and to have chronic health conditions compared to unexposed women. In unadjusted analyses, several nutrition and health markers were significantly different between opioid exposure groups. After controlling for covariates, women taking opioids had higher odds of Class II (OR = 1.6, 95% CI = 1.1–2.3) or III obesity (OR = 1.6, 95% CI = 1.1–2.5), and lower levels of serum folate, iron, and transferrin saturation. Reproductive-age women taking prescription opioids may be at risk for poorer nutritional and cardiometabolic health. Future research is needed to explore whether nutritional status impacts maternal–fetal outcomes for women exposed to opioids during pregnancy. MDPI 2023-04-14 /pmc/articles/PMC10144164/ /pubmed/37111110 http://dx.doi.org/10.3390/nu15081891 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hohman, Emily E.
Corr, Tammy E.
Kawasaki, Sarah
Savage, Jennifer S.
Symons Downs, Danielle
Nutritional Status Differs by Prescription Opioid Use among Women of Reproductive Age: NHANES 1999–2018
title Nutritional Status Differs by Prescription Opioid Use among Women of Reproductive Age: NHANES 1999–2018
title_full Nutritional Status Differs by Prescription Opioid Use among Women of Reproductive Age: NHANES 1999–2018
title_fullStr Nutritional Status Differs by Prescription Opioid Use among Women of Reproductive Age: NHANES 1999–2018
title_full_unstemmed Nutritional Status Differs by Prescription Opioid Use among Women of Reproductive Age: NHANES 1999–2018
title_short Nutritional Status Differs by Prescription Opioid Use among Women of Reproductive Age: NHANES 1999–2018
title_sort nutritional status differs by prescription opioid use among women of reproductive age: nhanes 1999–2018
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144164/
https://www.ncbi.nlm.nih.gov/pubmed/37111110
http://dx.doi.org/10.3390/nu15081891
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