Self-Assembly Nanostructure of Myristoylated ω-Conotoxin MVIIA Increases the Duration of Efficacy and Reduces Side Effects

Chronic pain is one of the most prevalent health problems worldwide. An alternative to suppress or alleviate chronic pain is the use of peptide drugs that block N-type Ca(2+) channels (Ca(v)2.2), such as ω-conotoxin MVIIA. Nevertheless, the narrow therapeutic window, severe neurological side effects...

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Detalles Bibliográficos
Autores principales: Ding, Xiufang, Wang, Yue, Zhang, Sida, Zhang, Ruihua, Chen, Dong, Chen, Long, Zhang, Yu, Luo, Shi-Zhong, Xu, Jianfu, Pei, Chengxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144222/
https://www.ncbi.nlm.nih.gov/pubmed/37103368
http://dx.doi.org/10.3390/md21040229

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