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ZBP1 Protects Against mtDNA-Induced Myocardial Inflammation in Failing Hearts

Mitochondrial DNA (mtDNA)-induced myocardial inflammation is intimately involved in cardiac remodeling. ZBP1 (Z-DNA binding protein 1) is a pattern recognition receptor positively regulating inflammation in response to mtDNA in inflammatory cells, fibroblasts, and endothelial cells. However, the rol...

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Detalles Bibliográficos
Autores principales:	Enzan, Nobuyuki, Matsushima, Shouji, Ikeda, Soichiro, Okabe, Kosuke, Ishikita, Akihito, Yamamoto, Taishi, Sada, Masashi, Miyake, Ryo, Tsutsui, Yoshitomo, Nishimura, Ryohei, Toyohara, Takayuki, Ikeda, Yuki, Shojima, Yoko, Miyamoto, Hiroko Deguchi, Tadokoro, Tomonori, Ikeda, Masataka, Abe, Kohtaro, Ide, Tomomi, Kinugawa, Shintaro, Tsutsui, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144299/ https://www.ncbi.nlm.nih.gov/pubmed/36974722 http://dx.doi.org/10.1161/CIRCRESAHA.122.322227

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