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Antiseizure Properties of Histamine H(3) Receptor Antagonists Belonging 3,4-Dihydroquinolin-2(1H)-Ones

H(3)R is becoming an attractive and promising target for epilepsy treatment as well as the discovery of antiepileptics. In this work, a series of 6-aminoalkoxy-3,4-dihydroquinolin-2(1H)-ones was prepared to screen their H(3)R antagonistic activities and antiseizure effects. The majority of the targe...

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Detalles Bibliográficos
Autores principales: Hua, Yi, Song, Mingxia, Guo, Qiaoyue, Luo, Yiqin, Deng, Xianqing, Huang, Yushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144301/
https://www.ncbi.nlm.nih.gov/pubmed/37110645
http://dx.doi.org/10.3390/molecules28083408