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In Silico Design of a Chimeric Humanized L-asparaginase

Acute lymphoblastic leukemia (ALL) is the most common cancer among children worldwide, characterized by an overproduction of undifferentiated lymphoblasts in the bone marrow. The treatment of choice for this disease is the enzyme L-asparaginase (ASNase) from bacterial sources. ASNase hydrolyzes circ...

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Detalles Bibliográficos
Autores principales:	Pedroso, Alejandro, Herrera Belén, Lisandra, Beltrán, Jorge F., Castillo, Rodrigo L., Pessoa, Adalberto, Pedroso, Enrique, Farías, Jorge G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144303/ https://www.ncbi.nlm.nih.gov/pubmed/37108713 http://dx.doi.org/10.3390/ijms24087550

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