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Identification of 7-Ketocholesterol-Modulated Pathways and Sterculic Acid Protective Effect in Retinal Pigmented Epithelium Cells by Using Genome-Wide Transcriptomic Analysis

Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries. AMD is characterized by the formation of lipidic deposits between the retinal pigment epithelium (RPE) and the choroid called drusen. 7-Ketocholesterol (7KCh), an oxidized-cholesterol derivative, is clos...

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Detalles Bibliográficos
Autores principales: Pariente, Ana, Pérez-Sala, Álvaro, Ochoa, Rodrigo, Bobadilla, Miriam, Villanueva-Martínez, Ángela, Peláez, Rafael, Larráyoz, Ignacio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144535/
https://www.ncbi.nlm.nih.gov/pubmed/37108627
http://dx.doi.org/10.3390/ijms24087459

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