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Identification of 7-Ketocholesterol-Modulated Pathways and Sterculic Acid Protective Effect in Retinal Pigmented Epithelium Cells by Using Genome-Wide Transcriptomic Analysis
Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries. AMD is characterized by the formation of lipidic deposits between the retinal pigment epithelium (RPE) and the choroid called drusen. 7-Ketocholesterol (7KCh), an oxidized-cholesterol derivative, is clos...
Autores principales: | Pariente, Ana, Pérez-Sala, Álvaro, Ochoa, Rodrigo, Bobadilla, Miriam, Villanueva-Martínez, Ángela, Peláez, Rafael, Larráyoz, Ignacio M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144535/ https://www.ncbi.nlm.nih.gov/pubmed/37108627 http://dx.doi.org/10.3390/ijms24087459 |
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