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Targeting Protein-Protein Interactions to Inhibit Cyclin-Dependent Kinases

Cyclin-dependent kinases (CDKs) play diverse and critical roles in normal cells and may be exploited as targets in cancer therapeutic strategies. CDK4 inhibitors are currently approved for treatment in advanced breast cancer. This success has led to continued pursuit of targeting other CDKs. One cha...

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Detalles Bibliográficos
Autor principal: Klein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10144709/
https://www.ncbi.nlm.nih.gov/pubmed/37111276
http://dx.doi.org/10.3390/ph16040519