Cargando…

Revolutionizing Drug Delivery and Therapeutics: The Biomedical Applications of Conductive Polymers and Composites-Based Systems

The first conductive polymers (CPs) were developed during the 1970s as a unique class of organic substances with properties that are electrically and optically comparable to those of inorganic semiconductors and metals while also exhibiting the desirable traits of conventional polymers. CPs have bec...

Descripción completa

Detalles Bibliográficos
Autores principales: Paramshetti, Sharanya, Angolkar, Mohit, Al Fatease, Adel, Alshahrani, Sultan M., Hani, Umme, Garg, Ankitha, Ravi, Gundawar, Osmani, Riyaz Ali M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145001/
https://www.ncbi.nlm.nih.gov/pubmed/37111689
http://dx.doi.org/10.3390/pharmaceutics15041204
_version_ 1785034228750090240
author Paramshetti, Sharanya
Angolkar, Mohit
Al Fatease, Adel
Alshahrani, Sultan M.
Hani, Umme
Garg, Ankitha
Ravi, Gundawar
Osmani, Riyaz Ali M.
author_facet Paramshetti, Sharanya
Angolkar, Mohit
Al Fatease, Adel
Alshahrani, Sultan M.
Hani, Umme
Garg, Ankitha
Ravi, Gundawar
Osmani, Riyaz Ali M.
author_sort Paramshetti, Sharanya
collection PubMed
description The first conductive polymers (CPs) were developed during the 1970s as a unique class of organic substances with properties that are electrically and optically comparable to those of inorganic semiconductors and metals while also exhibiting the desirable traits of conventional polymers. CPs have become a subject of intensive research due to their exceptional qualities, such as high mechanical and optical properties, tunable electrical characteristics, ease of synthesis and fabrication, and higher environmental stability than traditional inorganic materials. Although conducting polymers have several limitations in their pure state, coupling with other materials helps overcome these drawbacks. Owing to the fact that various types of tissues are responsive to stimuli and electrical fields has made these smart biomaterials attractive for a range of medical and biological applications. For various applications, including the delivery of drugs, biosensors, biomedical implants, and tissue engineering, electrical CPs and composites have attracted significant interest in both research and industry. These bimodalities can be programmed to respond to both internal and external stimuli. Additionally, these smart biomaterials have the ability to deliver drugs in various concentrations and at an extensive range. This review briefly discusses the commonly used CPs, composites, and their synthesis processes. Further highlights the importance of these materials in drug delivery along with their applicability in various delivery systems.
format Online
Article
Text
id pubmed-10145001
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-101450012023-04-29 Revolutionizing Drug Delivery and Therapeutics: The Biomedical Applications of Conductive Polymers and Composites-Based Systems Paramshetti, Sharanya Angolkar, Mohit Al Fatease, Adel Alshahrani, Sultan M. Hani, Umme Garg, Ankitha Ravi, Gundawar Osmani, Riyaz Ali M. Pharmaceutics Review The first conductive polymers (CPs) were developed during the 1970s as a unique class of organic substances with properties that are electrically and optically comparable to those of inorganic semiconductors and metals while also exhibiting the desirable traits of conventional polymers. CPs have become a subject of intensive research due to their exceptional qualities, such as high mechanical and optical properties, tunable electrical characteristics, ease of synthesis and fabrication, and higher environmental stability than traditional inorganic materials. Although conducting polymers have several limitations in their pure state, coupling with other materials helps overcome these drawbacks. Owing to the fact that various types of tissues are responsive to stimuli and electrical fields has made these smart biomaterials attractive for a range of medical and biological applications. For various applications, including the delivery of drugs, biosensors, biomedical implants, and tissue engineering, electrical CPs and composites have attracted significant interest in both research and industry. These bimodalities can be programmed to respond to both internal and external stimuli. Additionally, these smart biomaterials have the ability to deliver drugs in various concentrations and at an extensive range. This review briefly discusses the commonly used CPs, composites, and their synthesis processes. Further highlights the importance of these materials in drug delivery along with their applicability in various delivery systems. MDPI 2023-04-10 /pmc/articles/PMC10145001/ /pubmed/37111689 http://dx.doi.org/10.3390/pharmaceutics15041204 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Paramshetti, Sharanya
Angolkar, Mohit
Al Fatease, Adel
Alshahrani, Sultan M.
Hani, Umme
Garg, Ankitha
Ravi, Gundawar
Osmani, Riyaz Ali M.
Revolutionizing Drug Delivery and Therapeutics: The Biomedical Applications of Conductive Polymers and Composites-Based Systems
title Revolutionizing Drug Delivery and Therapeutics: The Biomedical Applications of Conductive Polymers and Composites-Based Systems
title_full Revolutionizing Drug Delivery and Therapeutics: The Biomedical Applications of Conductive Polymers and Composites-Based Systems
title_fullStr Revolutionizing Drug Delivery and Therapeutics: The Biomedical Applications of Conductive Polymers and Composites-Based Systems
title_full_unstemmed Revolutionizing Drug Delivery and Therapeutics: The Biomedical Applications of Conductive Polymers and Composites-Based Systems
title_short Revolutionizing Drug Delivery and Therapeutics: The Biomedical Applications of Conductive Polymers and Composites-Based Systems
title_sort revolutionizing drug delivery and therapeutics: the biomedical applications of conductive polymers and composites-based systems
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145001/
https://www.ncbi.nlm.nih.gov/pubmed/37111689
http://dx.doi.org/10.3390/pharmaceutics15041204
work_keys_str_mv AT paramshettisharanya revolutionizingdrugdeliveryandtherapeuticsthebiomedicalapplicationsofconductivepolymersandcompositesbasedsystems
AT angolkarmohit revolutionizingdrugdeliveryandtherapeuticsthebiomedicalapplicationsofconductivepolymersandcompositesbasedsystems
AT alfateaseadel revolutionizingdrugdeliveryandtherapeuticsthebiomedicalapplicationsofconductivepolymersandcompositesbasedsystems
AT alshahranisultanm revolutionizingdrugdeliveryandtherapeuticsthebiomedicalapplicationsofconductivepolymersandcompositesbasedsystems
AT haniumme revolutionizingdrugdeliveryandtherapeuticsthebiomedicalapplicationsofconductivepolymersandcompositesbasedsystems
AT gargankitha revolutionizingdrugdeliveryandtherapeuticsthebiomedicalapplicationsofconductivepolymersandcompositesbasedsystems
AT ravigundawar revolutionizingdrugdeliveryandtherapeuticsthebiomedicalapplicationsofconductivepolymersandcompositesbasedsystems
AT osmaniriyazalim revolutionizingdrugdeliveryandtherapeuticsthebiomedicalapplicationsofconductivepolymersandcompositesbasedsystems