Cargando…

Genomic Analysis of Amphioxus Reveals a Wide Range of Fragments Homologous to Viral Sequences

Amphioxus species are considered living fossils and are important in the evolutionary study of chordates and vertebrates. To explore viral homologous sequences, a high-quality annotated genome of the Beihai amphioxus (Branchiostoma belcheri beihai) was examined using virus sequence queries. In this...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Qiao, Peng, Fang, Xiong, Qing, Xu, Kejin, Yang, Kevin Yi, Wang, Mingqiang, Wu, Zhitian, Li, Shanying, Cheng, Xiaorui, Rao, Xinjie, Wang, Yuyouye, Tsui, Stephen Kwok-Wing, Zeng, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145014/
https://www.ncbi.nlm.nih.gov/pubmed/37112889
http://dx.doi.org/10.3390/v15040909
Descripción
Sumario:Amphioxus species are considered living fossils and are important in the evolutionary study of chordates and vertebrates. To explore viral homologous sequences, a high-quality annotated genome of the Beihai amphioxus (Branchiostoma belcheri beihai) was examined using virus sequence queries. In this study, 347 homologous fragments (HFs) of viruses were identified in the genome of B. belcheri beihai, of which most were observed on 21 genome assembly scaffolds. HFs were preferentially located within protein-coding genes, particularly in their CDS regions and promoters. A range of amphioxus genes with a high frequency of HFs is proposed, including histone-related genes that are homologous to the Histone or Histone H2B domains of viruses. Together, this comprehensive analysis of viral HFs provides insights into the neglected role of viral integration in the evolution of amphioxus.