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Improvement of the Surface Properties of Polyether Ether Ketone via Arc Evaporation for Biomedical Applications

Polyether ether ketone is a bioinert polymer, that is of high interest in research and medicine as an alternative material for the replacement of bone implants made of metal. The biggest deficit of this polymer is its hydrophobic surface, which is rather unfavorable for cell adhesion and thus leads...

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Autores principales: Fedotkin, Alexander Y., Akimchenko, Igor O., Tran, Tuan-Hoang, Shugurov, Artur R., Shesterikov, Evgeniy V., Kozelskaya, Anna I., Rutkowski, Sven, Tverdokhlebov, Sergei I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145034/
https://www.ncbi.nlm.nih.gov/pubmed/37109826
http://dx.doi.org/10.3390/ma16082990
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author Fedotkin, Alexander Y.
Akimchenko, Igor O.
Tran, Tuan-Hoang
Shugurov, Artur R.
Shesterikov, Evgeniy V.
Kozelskaya, Anna I.
Rutkowski, Sven
Tverdokhlebov, Sergei I.
author_facet Fedotkin, Alexander Y.
Akimchenko, Igor O.
Tran, Tuan-Hoang
Shugurov, Artur R.
Shesterikov, Evgeniy V.
Kozelskaya, Anna I.
Rutkowski, Sven
Tverdokhlebov, Sergei I.
author_sort Fedotkin, Alexander Y.
collection PubMed
description Polyether ether ketone is a bioinert polymer, that is of high interest in research and medicine as an alternative material for the replacement of bone implants made of metal. The biggest deficit of this polymer is its hydrophobic surface, which is rather unfavorable for cell adhesion and thus leads to slow osseointegration. In order to address this drawback, 3D-printed and polymer extruded polyether ether ketone disc samples that were surface-modified with titanium thin films of four different thicknesses via arc evaporation were investigated and compared with non-modified disc samples. Depending on the modification time, the thickness of the coatings ranged from 40 nm to 450 nm. The 3D-printing process does not affect the surface or bulk properties of polyether ether ketone. It turned out that the chemical composition of the coatings obtained did not depend on the type of substrate. Titanium coatings contain titanium oxide and have an amorphous structure. Microdroplets formed on the sample surfaces during treatment with an arc evaporator contain a rutile phase in their composition. Surface modification of the samples via arc evaporation resulted in an increase in the arithmetic mean roughness from 20 nm to 40 nm for the extruded samples and from 40 nm to 100 nm for the 3D-printed samples, with the mean height difference increasing from 100 nm to 250 nm and from 140 nm to 450 nm. Despite the fact that the hardness and reduced elastic modulus of the unmodified 3D-printed samples (0.33 GPa and 5.80 GPa) are higher than those of the unmodified extruded samples (0.22 GPa and 3.40 GPa), the surface properties of the samples after modification are approximately the same. The water contact angles of the polyether ether ketone sample surfaces decrease from 70° to 10° for the extruded samples and from 80° to 6° for the 3D-printed samples as the thickness of the titanium coating increases, making this type of coating promising for biomedical applications.
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spelling pubmed-101450342023-04-29 Improvement of the Surface Properties of Polyether Ether Ketone via Arc Evaporation for Biomedical Applications Fedotkin, Alexander Y. Akimchenko, Igor O. Tran, Tuan-Hoang Shugurov, Artur R. Shesterikov, Evgeniy V. Kozelskaya, Anna I. Rutkowski, Sven Tverdokhlebov, Sergei I. Materials (Basel) Article Polyether ether ketone is a bioinert polymer, that is of high interest in research and medicine as an alternative material for the replacement of bone implants made of metal. The biggest deficit of this polymer is its hydrophobic surface, which is rather unfavorable for cell adhesion and thus leads to slow osseointegration. In order to address this drawback, 3D-printed and polymer extruded polyether ether ketone disc samples that were surface-modified with titanium thin films of four different thicknesses via arc evaporation were investigated and compared with non-modified disc samples. Depending on the modification time, the thickness of the coatings ranged from 40 nm to 450 nm. The 3D-printing process does not affect the surface or bulk properties of polyether ether ketone. It turned out that the chemical composition of the coatings obtained did not depend on the type of substrate. Titanium coatings contain titanium oxide and have an amorphous structure. Microdroplets formed on the sample surfaces during treatment with an arc evaporator contain a rutile phase in their composition. Surface modification of the samples via arc evaporation resulted in an increase in the arithmetic mean roughness from 20 nm to 40 nm for the extruded samples and from 40 nm to 100 nm for the 3D-printed samples, with the mean height difference increasing from 100 nm to 250 nm and from 140 nm to 450 nm. Despite the fact that the hardness and reduced elastic modulus of the unmodified 3D-printed samples (0.33 GPa and 5.80 GPa) are higher than those of the unmodified extruded samples (0.22 GPa and 3.40 GPa), the surface properties of the samples after modification are approximately the same. The water contact angles of the polyether ether ketone sample surfaces decrease from 70° to 10° for the extruded samples and from 80° to 6° for the 3D-printed samples as the thickness of the titanium coating increases, making this type of coating promising for biomedical applications. MDPI 2023-04-09 /pmc/articles/PMC10145034/ /pubmed/37109826 http://dx.doi.org/10.3390/ma16082990 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fedotkin, Alexander Y.
Akimchenko, Igor O.
Tran, Tuan-Hoang
Shugurov, Artur R.
Shesterikov, Evgeniy V.
Kozelskaya, Anna I.
Rutkowski, Sven
Tverdokhlebov, Sergei I.
Improvement of the Surface Properties of Polyether Ether Ketone via Arc Evaporation for Biomedical Applications
title Improvement of the Surface Properties of Polyether Ether Ketone via Arc Evaporation for Biomedical Applications
title_full Improvement of the Surface Properties of Polyether Ether Ketone via Arc Evaporation for Biomedical Applications
title_fullStr Improvement of the Surface Properties of Polyether Ether Ketone via Arc Evaporation for Biomedical Applications
title_full_unstemmed Improvement of the Surface Properties of Polyether Ether Ketone via Arc Evaporation for Biomedical Applications
title_short Improvement of the Surface Properties of Polyether Ether Ketone via Arc Evaporation for Biomedical Applications
title_sort improvement of the surface properties of polyether ether ketone via arc evaporation for biomedical applications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145034/
https://www.ncbi.nlm.nih.gov/pubmed/37109826
http://dx.doi.org/10.3390/ma16082990
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