Cargando…

Managing Fetal Ovarian Cysts: Clinical Experience with a Rare Disorder

Background and Objectives: Fetal ovarian cysts (FOCs) are a very rare pathology that can be associated with maternal–fetal and neonatal complications. The aim of this study was to assess the influence of ultrasound characteristics on FOC evolution and therapeutic management. Materials and Methods: W...

Descripción completa

Detalles Bibliográficos
Autores principales: Melinte-Popescu, Alina-Sinziana, Popa, Radu-Florin, Harabor, Valeriu, Nechita, Aurel, Harabor, AnaMaria, Adam, Ana-Maria, Vasilache, Ingrid-Andrada, Melinte-Popescu, Marian, Vaduva, Cristian, Socolov, Demetra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145213/
https://www.ncbi.nlm.nih.gov/pubmed/37109673
http://dx.doi.org/10.3390/medicina59040715
_version_ 1785034279197081600
author Melinte-Popescu, Alina-Sinziana
Popa, Radu-Florin
Harabor, Valeriu
Nechita, Aurel
Harabor, AnaMaria
Adam, Ana-Maria
Vasilache, Ingrid-Andrada
Melinte-Popescu, Marian
Vaduva, Cristian
Socolov, Demetra
author_facet Melinte-Popescu, Alina-Sinziana
Popa, Radu-Florin
Harabor, Valeriu
Nechita, Aurel
Harabor, AnaMaria
Adam, Ana-Maria
Vasilache, Ingrid-Andrada
Melinte-Popescu, Marian
Vaduva, Cristian
Socolov, Demetra
author_sort Melinte-Popescu, Alina-Sinziana
collection PubMed
description Background and Objectives: Fetal ovarian cysts (FOCs) are a very rare pathology that can be associated with maternal–fetal and neonatal complications. The aim of this study was to assess the influence of ultrasound characteristics on FOC evolution and therapeutic management. Materials and Methods: We included cases admitted to our perinatal tertiary center between August 2016 and December 2022 with a prenatal or postnatal ultrasound evaluation indicative of FOC. We retrospectively analyzed the pre- and postnatal medical records, sonographic findings, operation protocols, and pathology reports. Results: This study investigated 20 cases of FOCs, of which 17 (85%) were diagnosed prenatally and 3 (15%) postnatally. The mean size of prenatally diagnosed ovarian cysts was 34.64 ± 12.53 mm for simple ovarian cysts and 55.16 ± 21.01 mm for complex ovarian cysts (p = 0.01). The simple FOCs ≤ 4 cm underwent resorption (n = 7, 70%) or size reduction (n = 3, 30%) without complications. Only 1 simple FOC greater than 4 cm reduced its size during follow-up, while 2 cases (66.6%) were complicated with ovarian torsion. Complex ovarian cysts diagnosed prenatally underwent resorption in only 1 case (25%), reduced in size in 1 case (25%), and were complicated with ovarian torsion in 2 cases (50%). Moreover, 2 simple (66.6%) and 1 complex (33.3%) fetal ovarian cysts were postnatally diagnosed. All of these simple ovarian cysts had a maximum diameter of ≤4 cm, and all of them underwent size reduction. The complex ovarian cyst of 4 cm underwent resorption during follow-up. Conclusions: Symptomatic neonatal ovarian cysts, as well as those that grow in size during sonographic follow-up, are in danger of ovarian torsion and should be operated on. Complex cysts and large cysts (with >4 cm diameter) could be followed up unless they become symptomatic or increase in dimensions during serial ultrasounds.
format Online
Article
Text
id pubmed-10145213
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-101452132023-04-29 Managing Fetal Ovarian Cysts: Clinical Experience with a Rare Disorder Melinte-Popescu, Alina-Sinziana Popa, Radu-Florin Harabor, Valeriu Nechita, Aurel Harabor, AnaMaria Adam, Ana-Maria Vasilache, Ingrid-Andrada Melinte-Popescu, Marian Vaduva, Cristian Socolov, Demetra Medicina (Kaunas) Article Background and Objectives: Fetal ovarian cysts (FOCs) are a very rare pathology that can be associated with maternal–fetal and neonatal complications. The aim of this study was to assess the influence of ultrasound characteristics on FOC evolution and therapeutic management. Materials and Methods: We included cases admitted to our perinatal tertiary center between August 2016 and December 2022 with a prenatal or postnatal ultrasound evaluation indicative of FOC. We retrospectively analyzed the pre- and postnatal medical records, sonographic findings, operation protocols, and pathology reports. Results: This study investigated 20 cases of FOCs, of which 17 (85%) were diagnosed prenatally and 3 (15%) postnatally. The mean size of prenatally diagnosed ovarian cysts was 34.64 ± 12.53 mm for simple ovarian cysts and 55.16 ± 21.01 mm for complex ovarian cysts (p = 0.01). The simple FOCs ≤ 4 cm underwent resorption (n = 7, 70%) or size reduction (n = 3, 30%) without complications. Only 1 simple FOC greater than 4 cm reduced its size during follow-up, while 2 cases (66.6%) were complicated with ovarian torsion. Complex ovarian cysts diagnosed prenatally underwent resorption in only 1 case (25%), reduced in size in 1 case (25%), and were complicated with ovarian torsion in 2 cases (50%). Moreover, 2 simple (66.6%) and 1 complex (33.3%) fetal ovarian cysts were postnatally diagnosed. All of these simple ovarian cysts had a maximum diameter of ≤4 cm, and all of them underwent size reduction. The complex ovarian cyst of 4 cm underwent resorption during follow-up. Conclusions: Symptomatic neonatal ovarian cysts, as well as those that grow in size during sonographic follow-up, are in danger of ovarian torsion and should be operated on. Complex cysts and large cysts (with >4 cm diameter) could be followed up unless they become symptomatic or increase in dimensions during serial ultrasounds. MDPI 2023-04-06 /pmc/articles/PMC10145213/ /pubmed/37109673 http://dx.doi.org/10.3390/medicina59040715 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Melinte-Popescu, Alina-Sinziana
Popa, Radu-Florin
Harabor, Valeriu
Nechita, Aurel
Harabor, AnaMaria
Adam, Ana-Maria
Vasilache, Ingrid-Andrada
Melinte-Popescu, Marian
Vaduva, Cristian
Socolov, Demetra
Managing Fetal Ovarian Cysts: Clinical Experience with a Rare Disorder
title Managing Fetal Ovarian Cysts: Clinical Experience with a Rare Disorder
title_full Managing Fetal Ovarian Cysts: Clinical Experience with a Rare Disorder
title_fullStr Managing Fetal Ovarian Cysts: Clinical Experience with a Rare Disorder
title_full_unstemmed Managing Fetal Ovarian Cysts: Clinical Experience with a Rare Disorder
title_short Managing Fetal Ovarian Cysts: Clinical Experience with a Rare Disorder
title_sort managing fetal ovarian cysts: clinical experience with a rare disorder
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145213/
https://www.ncbi.nlm.nih.gov/pubmed/37109673
http://dx.doi.org/10.3390/medicina59040715
work_keys_str_mv AT melintepopescualinasinziana managingfetalovariancystsclinicalexperiencewithararedisorder
AT poparaduflorin managingfetalovariancystsclinicalexperiencewithararedisorder
AT haraborvaleriu managingfetalovariancystsclinicalexperiencewithararedisorder
AT nechitaaurel managingfetalovariancystsclinicalexperiencewithararedisorder
AT haraboranamaria managingfetalovariancystsclinicalexperiencewithararedisorder
AT adamanamaria managingfetalovariancystsclinicalexperiencewithararedisorder
AT vasilacheingridandrada managingfetalovariancystsclinicalexperiencewithararedisorder
AT melintepopescumarian managingfetalovariancystsclinicalexperiencewithararedisorder
AT vaduvacristian managingfetalovariancystsclinicalexperiencewithararedisorder
AT socolovdemetra managingfetalovariancystsclinicalexperiencewithararedisorder