Vegetable Oil-Peroxidation Product ‘Hydroxynonenal’ Causes Hepatocyte Injury and Steatosis via Hsp70.1 and BHMT Disorders in the Monkey Liver

Hsp70.1 has a dual function as a chaperone protein and lysosomal stabilizer. In 2009, we reported that calpain-mediated cleavage of carbonylated Hsp70.1 causes neuronal death by inducing lysosomal rupture in the hippocampal CA1 neurons of monkeys after transient brain ischemia. Recently, we also rep...

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Detalles Bibliográficos
Autores principales: Yamashima, Tetsumori, Mori, Yurie, Seike, Takuya, Ahmed, Sharif, Boontem, Piyakarn, Li, Shihui, Oikawa, Shinji, Kobayashi, Hatasu, Yamashita, Tatsuya, Kikuchi, Mitsuru, Kaneko, Shuichi, Mizukoshi, Eishiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145254/
https://www.ncbi.nlm.nih.gov/pubmed/37111122
http://dx.doi.org/10.3390/nu15081904

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