Improved Tumor Control Following Radiosensitization with Ultrasound-Sensitive Oxygen Microbubbles and Tumor Mitochondrial Respiration Inhibitors in a Preclinical Model of Head and Neck Cancer

Tumor hypoxia (oxygen deficiency) is a major contributor to radiotherapy resistance. Ultrasound-sensitive microbubbles containing oxygen have been explored as a mechanism for overcoming tumor hypoxia locally prior to radiotherapy. Previously, our group demonstrated the ability to encapsulate and del...

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Detalles Bibliográficos
Autores principales: Lacerda, Quezia, Falatah, Hebah, Liu, Ji-Bin, Wessner, Corinne E., Oeffinger, Brian, Rochani, Ankit, Leeper, Dennis B., Forsberg, Flemming, Curry, Joseph M., Kaushal, Gagan, Keith, Scott W., O’Kane, Patrick, Wheatley, Margaret A., Eisenbrey, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145368/
https://www.ncbi.nlm.nih.gov/pubmed/37111787
http://dx.doi.org/10.3390/pharmaceutics15041302

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