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Pd(II) and Pt(II) Trinuclear Chelates with Spermidine: Selective Anticancer Activity towards TNBC-Sensitive and -Resistant to Cisplatin

Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance oft...

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Detalles Bibliográficos
Autores principales: Vojtek, Martin, Martins, Clara B., Ramos, Raquel, Duarte, Sara Gomes, Ferreira, Isabel M. P. L. V. O., Batista de Carvalho, Ana L. M., Marques, M. Paula M., Diniz, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145437/
https://www.ncbi.nlm.nih.gov/pubmed/37111690
http://dx.doi.org/10.3390/pharmaceutics15041205