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Determination and Comparison of Soybean Lecithin and Bovine Brain Plasmalogens Effects in Healthy Male Wistar Rats

The aim of this study was to investigate the effects of soybean lecithin and plasmalogens concentrating on a variety of physiological tests and biochemical analyses in healthy Wistar rats. For six weeks, male Wistar rats were given a standard diet that included plasmalogens or soybean lecithin. We m...

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Autores principales: Sidorova, Yuliya S., Sarkisyan, Varuzhan A., Petrov, Nikita A., Frolova, Yuliya V., Kochetkova, Alla A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145545/
https://www.ncbi.nlm.nih.gov/pubmed/37108804
http://dx.doi.org/10.3390/ijms24087643
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author Sidorova, Yuliya S.
Sarkisyan, Varuzhan A.
Petrov, Nikita A.
Frolova, Yuliya V.
Kochetkova, Alla A.
author_facet Sidorova, Yuliya S.
Sarkisyan, Varuzhan A.
Petrov, Nikita A.
Frolova, Yuliya V.
Kochetkova, Alla A.
author_sort Sidorova, Yuliya S.
collection PubMed
description The aim of this study was to investigate the effects of soybean lecithin and plasmalogens concentrating on a variety of physiological tests and biochemical analyses in healthy Wistar rats. For six weeks, male Wistar rats were given a standard diet that included plasmalogens or soybean lecithin. We measured anxiety levels, overall exploratory activity, short- and long-term memory, cognitive abilities, and grip strength. Lecithin increased significantly anxiety and enhanced memory and cognitive functions. Plasmalogens significantly improved appetite and increased grip strength. When compared to plasmalogens, lecithin significantly raised HDL levels while lowering LDL levels. The plasmalogens group showed a significant increase in the C16:0DMA/C16:0 ratio, which led us to assume that plasmalogen consumption could increase their synthesis in neural tissue. The study’s findings imply that, despite their various modes of action, soy lecithin and plasmalogens may both be significant nutritional components for enhancing cognitive functions.
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spelling pubmed-101455452023-04-29 Determination and Comparison of Soybean Lecithin and Bovine Brain Plasmalogens Effects in Healthy Male Wistar Rats Sidorova, Yuliya S. Sarkisyan, Varuzhan A. Petrov, Nikita A. Frolova, Yuliya V. Kochetkova, Alla A. Int J Mol Sci Article The aim of this study was to investigate the effects of soybean lecithin and plasmalogens concentrating on a variety of physiological tests and biochemical analyses in healthy Wistar rats. For six weeks, male Wistar rats were given a standard diet that included plasmalogens or soybean lecithin. We measured anxiety levels, overall exploratory activity, short- and long-term memory, cognitive abilities, and grip strength. Lecithin increased significantly anxiety and enhanced memory and cognitive functions. Plasmalogens significantly improved appetite and increased grip strength. When compared to plasmalogens, lecithin significantly raised HDL levels while lowering LDL levels. The plasmalogens group showed a significant increase in the C16:0DMA/C16:0 ratio, which led us to assume that plasmalogen consumption could increase their synthesis in neural tissue. The study’s findings imply that, despite their various modes of action, soy lecithin and plasmalogens may both be significant nutritional components for enhancing cognitive functions. MDPI 2023-04-21 /pmc/articles/PMC10145545/ /pubmed/37108804 http://dx.doi.org/10.3390/ijms24087643 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sidorova, Yuliya S.
Sarkisyan, Varuzhan A.
Petrov, Nikita A.
Frolova, Yuliya V.
Kochetkova, Alla A.
Determination and Comparison of Soybean Lecithin and Bovine Brain Plasmalogens Effects in Healthy Male Wistar Rats
title Determination and Comparison of Soybean Lecithin and Bovine Brain Plasmalogens Effects in Healthy Male Wistar Rats
title_full Determination and Comparison of Soybean Lecithin and Bovine Brain Plasmalogens Effects in Healthy Male Wistar Rats
title_fullStr Determination and Comparison of Soybean Lecithin and Bovine Brain Plasmalogens Effects in Healthy Male Wistar Rats
title_full_unstemmed Determination and Comparison of Soybean Lecithin and Bovine Brain Plasmalogens Effects in Healthy Male Wistar Rats
title_short Determination and Comparison of Soybean Lecithin and Bovine Brain Plasmalogens Effects in Healthy Male Wistar Rats
title_sort determination and comparison of soybean lecithin and bovine brain plasmalogens effects in healthy male wistar rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145545/
https://www.ncbi.nlm.nih.gov/pubmed/37108804
http://dx.doi.org/10.3390/ijms24087643
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