A Small Molecule Targeting the Intracellular Tyrosine Kinase Domain of ROR1 (KAN0441571C) Induced Significant Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells

The ROR1 receptor tyrosine kinase is expressed in embryonic tissues but is absent in normal adult tissues. ROR1 is of importance in oncogenesis and is overexpressed in several cancers, such as NSCLC. In this study, we evaluated ROR1 expression in NSCLC patients (N = 287) and the cytotoxic effects of...

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Detalles Bibliográficos
Autores principales: Ghaderi, Amineh, Okhovat, Mohammad-Ali, Lehto, Jemina, De Petris, Luigi, Manouchehri Doulabi, Ehsan, Kokhaei, Parviz, Zhong, Wen, Rassidakis, Georgios Z., Drakos, Elias, Moshfegh, Ali, Schultz, Johan, Olin, Thomas, Österborg, Anders, Mellstedt, Håkan, Hojjat-Farsangi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145660/
https://www.ncbi.nlm.nih.gov/pubmed/37111634
http://dx.doi.org/10.3390/pharmaceutics15041148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145660/
https://www.ncbi.nlm.nih.gov/pubmed/37111634
http://dx.doi.org/10.3390/pharmaceutics15041148

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