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Metabolomic Profiling of Asparagine Deprivation in Asparagine Synthetase Deficiency Patient-Derived Cells

The natural amino acid asparagine (Asn) is required by cells to sustain function and proliferation. Healthy cells can synthesize Asn through asparagine synthetase (ASNS) activity, whereas specific cancer and genetically diseased cells are forced to obtain asparagine from the extracellular environmen...

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Detalles Bibliográficos
Autores principales:	Chang, Mario C., Staklinski, Stephen J., Malut, Vinay R., Pierre, Geraldine L., Kilberg, Michael S., Merritt, Matthew E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145675/ https://www.ncbi.nlm.nih.gov/pubmed/37111157 http://dx.doi.org/10.3390/nu15081938

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