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The Epichloë festucae Antifungal Protein Efe-AfpA Has Activity against Numerous Plant Pathogens
Fungal plant pathogens can present major problems for most crop species. Currently, control of fungal diseases relies heavily on the use of fungicides. However, there are problems associated with fungicide use, including potential toxicity to non-target organisms and the development of resistance in...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145699/ https://www.ncbi.nlm.nih.gov/pubmed/37110250 http://dx.doi.org/10.3390/microorganisms11040828 |
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author | Fardella, Patrick A. Clarke, Bruce B. Belanger, Faith C. |
author_facet | Fardella, Patrick A. Clarke, Bruce B. Belanger, Faith C. |
author_sort | Fardella, Patrick A. |
collection | PubMed |
description | Fungal plant pathogens can present major problems for most crop species. Currently, control of fungal diseases relies heavily on the use of fungicides. However, there are problems associated with fungicide use, including potential toxicity to non-target organisms and the development of resistance in the target fungus. New strategies are being sought to reduce fungicide use. One area of active research is the potential use of antifungal proteins from various fungal species as alternatives or complements to traditional fungicides. An antifungal protein, Efe-AfpA, from the fungal endophyte Epichloë festucae was previously found to protect plants from the pathogen Clarireedia jacksonii, the causal agent of dollar spot disease. Here we report that Efe-AfpA also has inhibitory activity against other important plant pathogens. These results suggest that it may be possible to develop Efe-AfpA as a biofungicide to target a broad range of destructive plant pathogens. |
format | Online Article Text |
id | pubmed-10145699 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101456992023-04-29 The Epichloë festucae Antifungal Protein Efe-AfpA Has Activity against Numerous Plant Pathogens Fardella, Patrick A. Clarke, Bruce B. Belanger, Faith C. Microorganisms Article Fungal plant pathogens can present major problems for most crop species. Currently, control of fungal diseases relies heavily on the use of fungicides. However, there are problems associated with fungicide use, including potential toxicity to non-target organisms and the development of resistance in the target fungus. New strategies are being sought to reduce fungicide use. One area of active research is the potential use of antifungal proteins from various fungal species as alternatives or complements to traditional fungicides. An antifungal protein, Efe-AfpA, from the fungal endophyte Epichloë festucae was previously found to protect plants from the pathogen Clarireedia jacksonii, the causal agent of dollar spot disease. Here we report that Efe-AfpA also has inhibitory activity against other important plant pathogens. These results suggest that it may be possible to develop Efe-AfpA as a biofungicide to target a broad range of destructive plant pathogens. MDPI 2023-03-24 /pmc/articles/PMC10145699/ /pubmed/37110250 http://dx.doi.org/10.3390/microorganisms11040828 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Fardella, Patrick A. Clarke, Bruce B. Belanger, Faith C. The Epichloë festucae Antifungal Protein Efe-AfpA Has Activity against Numerous Plant Pathogens |
title | The Epichloë festucae Antifungal Protein Efe-AfpA Has Activity against Numerous Plant Pathogens |
title_full | The Epichloë festucae Antifungal Protein Efe-AfpA Has Activity against Numerous Plant Pathogens |
title_fullStr | The Epichloë festucae Antifungal Protein Efe-AfpA Has Activity against Numerous Plant Pathogens |
title_full_unstemmed | The Epichloë festucae Antifungal Protein Efe-AfpA Has Activity against Numerous Plant Pathogens |
title_short | The Epichloë festucae Antifungal Protein Efe-AfpA Has Activity against Numerous Plant Pathogens |
title_sort | epichloë festucae antifungal protein efe-afpa has activity against numerous plant pathogens |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145699/ https://www.ncbi.nlm.nih.gov/pubmed/37110250 http://dx.doi.org/10.3390/microorganisms11040828 |
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