The Effect of Sclerostin and Monoclonal Sclerostin Antibody Romosozumab on Osteogenesis and Osteoclastogenesis Mediated by Periodontal Ligament Fibroblasts

Sclerostin is a bone formation inhibitor produced by osteocytes. Although sclerostin is mainly expressed in osteocytes, it was also reported in periodontal ligament (PDL) fibroblasts, which are cells that play a role in both osteogenesis and osteoclastogenesis. Here, we assess the role of sclerostin...

Descripción completa

Detalles Bibliográficos
Autores principales: Pigeaud, Karina E., Rietveld, Melanie L., Witvliet, Aster F., Hogervorst, Jolanda M. A., Zhang, Chen, Forouzanfar, Tim, Bravenboer, Nathalie, Schoenmaker, Ton, de Vries, Teun J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145870/
https://www.ncbi.nlm.nih.gov/pubmed/37108735
http://dx.doi.org/10.3390/ijms24087574

Ejemplares similares

Ejemplares similares