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Bruch’s Membrane: A Key Consideration with Complement-Based Therapies for Age-Related Macular Degeneration

The complement system is crucial for immune surveillance, providing the body’s first line of defence against pathogens. However, an imbalance in its regulators can lead to inappropriate overactivation, resulting in diseases such as age-related macular degeneration (AMD), a leading cause of irreversi...

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Detalles Bibliográficos
Autores principales: Hammadi, Sarah, Tzoumas, Nikolaos, Ferrara, Mariantonia, Meschede, Ingrid Porpino, Lo, Katharina, Harris, Claire, Lako, Majlinda, Steel, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145879/
https://www.ncbi.nlm.nih.gov/pubmed/37109207
http://dx.doi.org/10.3390/jcm12082870