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Bruch’s Membrane: A Key Consideration with Complement-Based Therapies for Age-Related Macular Degeneration
The complement system is crucial for immune surveillance, providing the body’s first line of defence against pathogens. However, an imbalance in its regulators can lead to inappropriate overactivation, resulting in diseases such as age-related macular degeneration (AMD), a leading cause of irreversi...
Autores principales: | Hammadi, Sarah, Tzoumas, Nikolaos, Ferrara, Mariantonia, Meschede, Ingrid Porpino, Lo, Katharina, Harris, Claire, Lako, Majlinda, Steel, David H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145879/ https://www.ncbi.nlm.nih.gov/pubmed/37109207 http://dx.doi.org/10.3390/jcm12082870 |
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