A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis

The renal actions of parathyroid hormone (PTH) promote 1,25-vitamin D generation; however, the signaling mechanisms that control PTH-dependent vitamin D activation remain unknown. Here, we demonstrated that salt-inducible kinases (SIKs) orchestrated renal 1,25-vitamin D production downstream of PTH...

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Detalles Bibliográficos
Autores principales: Yoon, Sung-Hee, Meyer, Mark B., Arevalo, Carlos, Tekguc, Murat, Zhang, Chengcheng, Wang, Jialiang S., Castro Andrade, Christian D., Strauss, Katelyn, Sato, Tadatoshi, Benkusky, Nancy A., Lee, Seong Min, Berdeaux, Rebecca, Foretz, Marc, Sundberg, Thomas B., Xavier, Ramnik J., Adelmann, Charles H., Brooks, Daniel J., Anselmo, Anthony, Sadreyev, Ruslan I., Rosales, Ivy A., Fisher, David E., Gupta, Navin, Morizane, Ryuji, Greka, Anna, Pike, J. Wesley, Mannstadt, Michael, Wein, Marc N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145948/
https://www.ncbi.nlm.nih.gov/pubmed/36862513
http://dx.doi.org/10.1172/JCI163627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10145948/
https://www.ncbi.nlm.nih.gov/pubmed/36862513
http://dx.doi.org/10.1172/JCI163627

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