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Overexpression of Global Regulator SCrp Leads to the Discovery of New Angucyclines in Streptomyces sp. XS-16

Six angucyclines including three unreported compounds (1–3) were isolated from Streptomyces sp. XS-16 by overexpressing the native global regulator of SCrp (cyclic AMP receptor). The structures were characterized based on nuclear magnetic resonance (NMR) and spectrometry analysis and assisted by ele...

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Detalles Bibliográficos
Autores principales: Xu, Xiao, Zhang, Falei, Zhou, Luning, Chang, Yimin, Che, Qian, Zhu, Tianjiao, Li, Dehai, Zhang, Guojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146017/
https://www.ncbi.nlm.nih.gov/pubmed/37103379
http://dx.doi.org/10.3390/md21040240