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High-Throughput IgG Epitope Mapping of Tetanus Neurotoxin: Implications for Immunotherapy and Vaccine Design
Tetanus is an acute, fatal disease caused by exotoxins released from Clostridium tetani during infections. A protective humoral immune response can be induced by vaccinations with pediatric and booster combinatorial vaccines that contain inactivated tetanus neurotoxin (TeNT) as a major antigen. Alth...
Autores principales: | De-Simone, Salvatore G., Napoleão-Pêgo, Paloma, Lechuga, Guilherme C., Carvalho, João P. R. S., Gomes, Larissa R., Cardozo, Sergian V., Morel, Carlos M., Provance, David W., da Silva, Flavio R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146279/ https://www.ncbi.nlm.nih.gov/pubmed/37104177 http://dx.doi.org/10.3390/toxins15040239 |
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