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Development of Transdermal Oleogel Containing Olmesartan Medoxomil: Statistical Optimization and Pharmacological Evaluation
Olmesartan medoxomil (OLM) is a first-line antihypertensive drug with low oral bioavailability (28.6%). This study aimed to develop oleogel formulations to decrease OLM side effects and boost its therapeutic efficacy and bioavailability. OLM oleogel formulations were composed of Tween 20, Aerosil 20...
Autores principales: | El-Dahmy, Rania Moataz, Elsayed, Ibrahim, Hussein, Jihan, Althubiti, Mohammad, Almaimani, Riyad A., El-Readi, Mahmoud Zaki, Elbaset, Marawan A., Ibrahim, Bassant M. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146305/ https://www.ncbi.nlm.nih.gov/pubmed/37111569 http://dx.doi.org/10.3390/pharmaceutics15041083 |
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