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Design and Preclinical Evaluation of Nicotine–Stearic Acid Conjugate-Loaded Solid Lipid Nanoparticles for Transdermal Delivery: A Technical Note

This study aimed to develop and evaluate nicotine--stearic acid conjugate-loaded solid lipid nanoparticles (NSA-SLNs) for transdermal delivery in nicotine replacement therapy (NRT). Nicotine conjugation to stearic acid prior to SLN formulation greatly increased drug loading. SLNs loaded with a nicot...

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Detalles Bibliográficos
Autores principales:	Renukuntla, Jwala, Peterson-Sockwell, Samuel, Clark, Bradley A., Godage, Nipunika H., Gionfriddo, Emanuela, Bolla, Pradeep Kumar, Boddu, Sai H. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146358/ https://www.ncbi.nlm.nih.gov/pubmed/37111529 http://dx.doi.org/10.3390/pharmaceutics15041043

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