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Exploring the Fate of Antibody-Encoding pDNA after Intramuscular Electroporation in Mice

DNA-based antibody therapy seeks to administer the encoding nucleotide sequence rather than the antibody protein. To further improve the in vivo monoclonal antibody (mAb) expression, a better understanding of what happens after the administration of the encoding plasmid DNA (pDNA) is required. This...

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Detalles Bibliográficos
Autores principales:	Cuypers, Marie-Lynn, Geukens, Nick, Hollevoet, Kevin, Declerck, Paul, Dewilde, Maarten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146361/ https://www.ncbi.nlm.nih.gov/pubmed/37111645 http://dx.doi.org/10.3390/pharmaceutics15041160

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