Topical Protease Inhibitor Decreases Anal Carcinogenesis in a Transgenic Mouse Model of HPV Anal Disease

Anal cancer is a major health problem. This study seeks to determine if the topical protease inhibitor Saquinavir (SQV), is effective at the prevention of anal cancer in transgenic mice with established anal dysplasia. K14E6/E7 mice were entered into the study when the majority spontaneously develop...

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Detalles Bibliográficos
Autores principales: Gunder, Laura C., Johnson, Hillary R., Yao, Evan, Moyer, Tyra H., Green, Heather A., Sherer, Nathan, Zhang, Wei, Carchman, Evie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146494/
https://www.ncbi.nlm.nih.gov/pubmed/37112993
http://dx.doi.org/10.3390/v15041013

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