Mincle-GSDMD-mediated release of IL-1β small extracellular vesicles from hepatic macrophages in ethanol-induced liver injury

Macrophage-inducible C-type lectin (Mincle) is expressed on hepatic macrophages and senses ethanol (EtOH)-induced danger signals released from dying hepatocytes and promotes IL-1β production. However, it remains unclear what and how EtOH-induced Mincle ligands activate downstream signaling events to...

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Detalles Bibliográficos
Autores principales: Zhang, Quanri, Liu, Weiwei, Bulek, Katarzyna, Wang, Han, McMullen, Megan R., Wu, Xiaoqin, Welch, Nicole, Zhang, Renliang, Dasarathy, Jaividhya, Dasarathy, Srinivasan, Nagy, Laura E., Li, Xiaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146535/
https://www.ncbi.nlm.nih.gov/pubmed/37185170
http://dx.doi.org/10.1097/HC9.0000000000000114

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