N(6)-methyladenosine reader protein YTHDC1 regulates influenza A virus NS segment splicing and replication

N(6)-methyladenosine (m(6)A) modification on viral RNAs has a profound impact on infectivity. m(6)A is also a highly pervasive modification for influenza viral RNAs. However, its role in virus mRNA splicing is largely unknown. Here, we identify the m(6)A reader protein YTHDC1 as a host factor that a...

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Detalles Bibliográficos
Autores principales: Zhu, Yinxing, Wang, Ruifang, Zou, Jiahui, Tian, Shan, Yu, Luyao, Zhou, Yuanbao, Ran, Ying, Jin, Meilin, Chen, Huanchun, Zhou, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10146569/
https://www.ncbi.nlm.nih.gov/pubmed/37053288
http://dx.doi.org/10.1371/journal.ppat.1011305

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